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Praziquantel ("Prazi") the safest most effective medication on the market for treating flukes, it does not stress your pond fish or set back your filter. Plus, Prazi is an excellent treatment for internal worms in goldfish, koi and tropical fish. All it takes is just one treatment of Prazi and no water changes. We suggest treating with Prazi every spring to get your pond fish off to a great year! Treats 5,000 Gallons